Large Symbolics
As more and more applications use empty state pages with the big symbolic icons, it becomes clearer that the scaled up 16x16 symbolic icon is too heavily weighted for the view plus in the upscale the tricks we use for legibility at that small scale are on full view, which isn't always a great look. (This would apply to the shell OSD notifications, volume, brightness, etc. where a large symbolic is also used).
I don't think all the icons need a large variant, to tackle this we should figure out those places that are using a large symbolic and create an icon (if necessary) for those places and ship those icon as an asset--e.g. the shell, gnome-initial-setup
To tackle this I think we can just design a 32x32 icon that can upscale better and potentially cover a few large sizes: 64x64, 96x96 and 128x128, rather than design a big icon.